Protein analysis using mass spectrometry : accelerating protein biotherapeutics from lab to patient / edited by Mike S. Lee and Qin C. Ji.

Contemporary Protein Analysis by Ion Mobility Mass Spectrometry / Johannes PC Vissers, James I Langridge -- High-Resolution Accurate Mass Orbitrap and Its Application in Protein Therapeutics Bioanalysis / Hongxia Wang, Patrick Bennett  -- Current Methods for the Characterization of Posttranslational Modifications in Therapeutic Proteins Using Orbitrap Mass Spectrometry / Zhiqi Hao, Qiuting Hong, Fan Zhang, Shiaw-Lin Wu, Patrick Bennett -- Macro- to Micromolecular Quantitation of Proteins and Peptides by Mass Spectrometry / Suma Ramagiri, Brigitte Simons, Laura Baker -- Peptide and Protein Bioanalysis Using Integrated Column-to-Source Technology for High-Flow Nanospray / Shane R Needham, Gary A Valaskovic  -- Targeting the Right Protein Isoform: Mass Spectrometry-Based Proteomic Characterization of Alternative Splice Variants / Jiang Wu -- The Application of Immunoaffinity-Based Mass Spectrometry to Characterize Protein Biomarkers and Biotherapeutics / Bradley L Ackermann, Michael J Berna -- Semiquantification and Isotyping of Antidrug Antibodies by Immunocapture-LC/MS for Immunogenicity Assessment / Jianing Zeng, Hao Jiang, Linlin Luo -- Mass Spectrometry-Based Assay for High-Throughput and High-Sensitivity Biomarker Verification / Xuejiang Guo, Keqi Tang -- Monitoring Quality of Critical Reagents Used in Ligand Binding Assays with Liquid Chromatography Mass Spectrometry (LC-MS) / Brian Geist, Adrienne Clements-Egan, Tong-Yuan Yang -- Application of Liquid Chromatography-High Resolution Mass Spectrometry in the Quantification of Intact Proteins in Biological Fluids / Stanley (Weihua) Zhang, Jonathan Crowther, Wenying Jian -- LC-MS/MS Bioanalytical Method Development Strategy for Therapeutic Monoclonal Antibodies in Preclinical Studies / Hongyan Li, Timothy Heath, Christopher A James -- Generic Peptide Strategies for LC-MS/MS Bioanalysis of Human Monoclonal Antibody Drugs and Drug Candidates / Michael T Furlong -- Mass Spectrometry-Based Methodologies for Pharmacokinetic Characterization of Antibody Drug Conjugate Candidates During Drug Development / Yongjun Xue, Priya Sriraman, Matthew V Myers, Xiaomin Wang, Jian Chen, Brian Melo, Martha Vallejo, Stephen E Maxwell, Sekhar Surapaneni -- Sample Preparation Strategies for LC-MS Bioanalysis of Proteins / Long Yuan, Qin C Ji -- Characterization of Protein Therapeutics by Mass Spectrometry / Wei Wu, Hangtian Song, Thomas Slaney, Richard Ludwig, Li Tao, Tapan Das.

Includes bibliographical references and index.

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