Successful drug discovery. Volume 2 / edited by János Fischer and Wayne E. Childers.

HDAC Inhibitor Anticancer Drug Discovery. From DMSO to the Anticancer Compound SAHA, an Unusual Intellectual Pathway for Drug Design / Ronald Breslow -- Romidepsin and the Zinc-Binding Thiol Family of Natural Product HDAC Inhibitors / A Ganesan -- The Discovery and Development of Belinostat / Paul W Finn, Einars Loza, Elisabeth Carstensen -- Discovery and Development of Farydak (NVP-LBH589, Panobinostat) as an Anticancer Drug / Peter Atadja, Lawrence Perez -- Discovery and Development of HDAC Subtype Selective Inhibitor Chidamide: Potential Immunomodulatory Activity Against Cancers / Xian-Ping Lu, Zhi-Qiang Ning, Zhi-Bin Li, De-Si Pan, Song Shan, Xia Guo, Hai-Xiang Cao, Jin-Di Yu, Qian-Jiao Yang -- Steroidal CYP17 Inhibitor Anticancer Drug Discovery. Abiraterone Acetate (Zytiga®): An Inhibitor of CYP17 as a Therapeutic for Castration-Resistant Prostate Cancer / Gabriel M Belfort, Boyd L Harrison, Gabriel Martinez Botella -- Anti-Infective Drug Discoveries. Discovery of Delamanid for the Treatment of Multidrug-Resistant Pulmonary Tuberculosis / Hidetsugu Tsubouchi, Hirofumi Sasaki, Hiroshi Ishikawa, Makoto Matsumoto -- Sofosbuvir: The Discovery of a Curative Therapy for the Treatment of Hepatitis C Virus / Michael J Sofia -- Central Nervous System(CNS) Drug Discovery. The Discovery of the Antidepressant Vortioxetine and the Research that Uncovered Its Potential to Treat the Cognitive Dysfunction Associated with Depression / Benny Bang-Andersen, Christina Kurre Olsen, Connie Sanchéz -- Antiulcer Drug Discovery. Discovery of Vonoprazan Fumarate (TAK-438) as a Novel, Potent and Long-Lasting Potassium-Competitive Acid Blocker / Haruyuki Nishida -- Cross-Therapeutic Drug Discovery (Respiratory Diseases/Anticancer). Discovery and Development of Nintedanib: A Novel Antiangiogenic and Antifibrotic Agent / Gerald J Roth, Rudolf Binder, Florian Colbatzky, Claudia Dallinger, Rozsa Schlenker-Herceg, Frank Hilberg, Lutz Wollin, John Park, Alexander Pautsch, Rolf Kaiser.

Online resource; title from PDF title page (EBSCO, viewed November 16, 2016)

Includes bibliographical references and index.