Bugs as drugs : therapeutic microbes for the prevention and treatment of disease / edited by Robert A. Britton, Baylor College of Medicine, Molecular Virology and Microbiology, Houston, Texas, Patrice D. Cani, Université catholique de Louvain, Louvain Drug Research Institute, WELBIO-Walloon Excellence in Life Sciences, Brussels, Belgium.

Print version record.

Includes bibliographical references and index.

A. Traditional probiotic approaches. 1. Biochemical features of beneficial microbes : foundations for therapeutic microbiology / Melinda A. Engevik and James Versalovic -- 2. The genomic basis of lactobacilli as health-promoting organisms / Elisa Salvetti and Paul W. O'Toole -- 3. Bifidobacteria and their health-promoting effects / Claudio Hidalgo-Cantabrana, Susana Delgado, Lorena Ruiz, Patricia Ruas-Madiedo, Borja Sánchez, and Abelardo Margolles -- B. Next-generation bacteriotherapy : opportunities in chronic diseases. 4. Microbial interactions and interventions in colorectal cancer / Terence van Raay and Emma Allen-Vercoe -- 5. Microbial impact on host metabolism : opportunities for novel treatments of nutritional disorders? / Hubert Plovier and Patrice D. Cani -- 6. Therapeutic opportunities in the vaginal microbiome / Gregor Reid -- 7. Lung microbiota and its impact on the mucosal immune phenotype / Benjamin G. Wu and Leopoldo N. Segal -- 8. Microbiota, liver diseases, and alcohol / Anne-Marie Cassard, Philippe Gérard, and Gabriel Perlemuter -- 9. The potential of probiotics as a therapy for osteoporosis / Fraser L. Collins, Naiomy D. Rios-Arce, Jonathan D. Schepper, Narayanan Parameswaran, and Laura R. McCabe -- 10. Ecological therapeutic opportunities for oral diseases / Anilei Hoare, Philip D. Marsh, and Patricia I. Diaz -- C. Control of infectious disease by microbes. 11. Control of Clostridium difficile infection by defined microbial communities / James Collins and Jennifer M. Auchtung -- 12. Fecal microbiota transplantation : therapeutic potential for a multitude of diseases beyond Clostridium difficile / Guido J. Bakker and Max Nieuwdorp -- 13. Enterococci and their interactions with the intestinal microbiome / Krista Dubin and Eric G. Palmer -- D. Next-generation microbial therapeutics : tools and regulation. 14. Engineering diagnostic and therapeutic gut bacteria / Brian P. Landry and Jeffrey J. Tabor -- 15. Use of traditional and genetically modified probiotics in human health : what does the future hold? / Luis G. Bermúdez-Humarán and Philippe Langella -- 16. Genetic tools for the enhancement of probiotic properties / Laura Ortiz-Velez and Robert Britton -- 17. Genome editing of food-grade lactobacilli to develop therapeutic probiotics / Jan-Peter van Pijkeren and Rodolphe Barrangou -- 18. United States regulatory considerations for development of live biotherapeutic products as drugs / Sheila M. Dreher-Lesnick, Scott Stibitz, and Paul E. Carlson, Jr. -- E. Indirect strategies to target microbiome function for health. 19. Bacteriophage clinical use as antibacterial "drugs" : utility and precedent / Stephen T. Abedon -- 20. Modulation of the gastrointestinal microbiome with nondigestable fermentable carbohydrates to improve human health / Edward C. Deehan, Rebbeca M. Duar, Anissa M. Armet, Maria Elisa Perez-Muñoz, Mingliang Jin, and Jens Walter.

Examining the enormous potential of microbiome manipulation to improve health.

Online resource; title from digital title page (viewed on January 30, 2018).