Genome editing : the next step in gene therapy / edited by Prerna Pandey and Shiv Sanjeev

"American Society of Gene & Cell Therapy"--Cover.

Includes bibliographical references and index.

Gene editing 20 years later / Maria Jasin -- The development and use of zinc-finger nucleases / Dana Carroll -- The use and development of TAL effector nucleases / Alexandre Juillerat, Philippe Duchateau, Toni Cathomen, and Claudio Mussolino -- Genome editing for neuromuscular diseases / David G. Ousterout and Charles A. Gersbach -- Phage integrases for genome editing / Michele P. Calos -- Precise genome modification using triplex forming oligonucleotides and peptide nucleic acids / Raman Bahal, Anisha Gupta, and Peter M. Glazer -- Genome editing by Aptamer-Guided Gene Targeting (AGT) / Patrick Ruff and Francesca Storici -- Stimulation of AAV gene editing via DSB repair / Angela M. Mitchell, Rachel Moser, Richard Jude Samulski, and Matthew Louis Hirsch -- Engineered nucleases and trinucleotide repeat diseases / John H. Wilson, Christopher Moye, and David Mittelman -- Using engineered nucleases to create HIV- resistant cells / George Nicholas Llewellyn, Colin M. Exline, Nathalia Holt, and Paula M. Cannon -- Strategies to determine off-target effects of engineered nucleases / Eli J. Fine, Thomas James Cradick, and Gang Bao -- Cellular engineering and disease modeling with gene-editing nucleases / Mark J. Osborn and Jakub Tolar.